Basic information of MIR193A :
| Official Symbol of Gene | MIR193A |
| Species | Homo sapiens |
| Entrez Gene ID | 791013 |
| Official Full Name | microRNA mir-193a |
| Also known as | MIRN193A; mir-193a; bta-mir-193a |
| Gene Type | ncRNA |
| dbXrefs | Ensembl:ENSBTAG00000029955 miRBase:MI0005014 |
| Map Location | chromosome: 19 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | qRT-PCR |
| Disease | MS |
| Disease subtype | MS |
| Population | NA |
| Sample Size | 30MS |
Literature information of multiple sclerosis :
| Pubmed ID | 36529069 |
| Year | 2022 |
| Title | Dysregulation of miR-193a serves as a potential contributor to MS pathogenesis via affecting RhoA and Rock1 |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | Results showed that miR-193a was decreased while RhoA and ROCK1 were up-regulated in PBMCs obtained from patients with MS compared to the control group. It was also revealed that miR-193a transfection reduced RhoA and ROCK1 expression at mRNA and protein levels. |
| Mechanism/Pathway | At present, microRNAs (miRNAs) are considered not only a diagnostic and prognostic indicator of diseases but also a new goal in gene therapy. |
