Basic information of TOB1 :
| Official Symbol of Gene | TOB1 |
| Species | Homo sapiens |
| Entrez Gene ID | 10140 |
| Official Full Name | transducer of ERBB2, 1 |
| Also known as | N/A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000141232 MIM:605523; AllianceGenome:HGNC:11979 |
| Map Location | 17q21.33 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | NA |
| Detected Method | RT-PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | NA |
| Sample Size | NA |
Literature information of multiple sclerosis :
| Pubmed ID | 18689680 |
| Year | 2008 |
| Title | Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological event |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Phenotypic risk |
| Result | Finally, a genetic association was observed between TOB1 variation and MS progression in an independent cohort. |
| Mechanism/Pathway | Currently there are no prognostic biological markers that accurately predict conversion of CIS to clini-cally definite MS (CDMS). |
