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Basic information of MICB :

Official Symbol of Gene MICB
Species Homo sapiens
Entrez Gene ID 4277
Official Full Name MHC class I polypeptide-related sequence B
Also known as PERB11.2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000204516 IMGT/GENE-DB:MICB; MIM:602436; AllianceGenome:HGNC:7091
Map Location N/A

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail NA
Detected Method RT-PCR
Disease MS
Disease subtype N/A
Population NA
Sample Size 48 MS/48Health

Literature information of multiple sclerosis :

Pubmed ID 22184268
Year 2011
Title MICB Gene Expression on Peripheral Blood Mononuclear Cells and Susceptibility to Multiple Sclerosis in North of Iran

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result It is concluded that the high expression of MICB gene in MS patients is an important criterion of MS disease that it may be due to the interaction between MICB and its receptor on CD8 +T or NK cells.
Mechanism/Pathway N/A