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Basic information of SERTAD1 :

Official Symbol of Gene SERTAD1
Species Homo sapiens
Entrez Gene ID 29950
Official Full Name SERTA domain containing 1
Also known as SEI1; TRIPBR1; TRIP-Br1
Gene Type protein coding
dbXrefs Ensembl:ENSG00000197019 MIM:617850; AllianceGenome:HGNC:17932
Map Location 19q13.2

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail N/A
Detected Method N/A
Disease MS
Disease subtype N/A
Population Swedish, caucasian patients
Sample Size five female

Literature information of multiple sclerosis :

Pubmed ID 34676774
Year 2021
Title Deep characterization of paired chromatin and transcriptomes in four immune cell types from multiple sclerosis patients

Results of multiple sclerosis :

Expression down-regulated
Risk type treatment risk
Result Gene expression of SERTAD1 was downregulated in RR, and CCDC115 was upregulated in RR.
Mechanism/Pathway SERTAD1 acts at E2F-responsive promoters.