Basic information of TNFSF10 :
| Official Symbol of Gene | TNFSF10 |
| Species | Homo sapiens |
| Entrez Gene ID | 8743 |
| Official Full Name | TNF superfamily member 10 |
| Also known as | TL2; APO2L; CD253; TANCR; TRAIL; Apo-2L; TNLG6A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000121858 MIM:603598; AllianceGenome:HGNC:11925 |
| Map Location | 3q26.31 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | N/A |
| Detected Method | Real-time quantitative RT-PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Iran |
| Sample Size | 50 relapse remitting MS patients and 50 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 27472871 |
| Year | 2016 |
| Title | TRAIL gene expression analysis in multiple sclerosis patients |
Results of multiple sclerosis :
| Expression | N/A |
| Risk type | disease risk |
| Result | No statistically significant difference was found in TRAIL mRNA expression between MS patients and controls (p >0.05). |
| Mechanism/Pathway | IFNb may have stimulatory effects on immunoregulatory function of TRAIL, so TRAIL can be a biomarker to follow up response to interferon beta. |
