Basic information of EXTL3 :
| Official Symbol of Gene | EXTL3 |
| Species | Homo sapiens |
| Entrez Gene ID | 2137 |
| Official Full Name | exostosin like glycosyltransferase 3 |
| Also known as | RPR; BOTV; REGR; EXTR1; ISDNA; EXTL1L |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000012232 MIM:605744; AllianceGenome:HGNC:3518 |
| Map Location | 8p21.1 |
Sample information of multiple sclerosis:
| Detected Sample | cerebrospinal fluid |
| Sample Detail | NA |
| Detected Method | RT-qPCR |
| Disease | RRMS |
| Disease subtype | N/A |
| Population | RRMS |
| Sample Size | 5RRMS+5control |
Literature information of multiple sclerosis :
| Pubmed ID | 33876425 |
| Year | 2021 |
| Title | Temporal overexpression of IL-22 and Reg3γ differentially impacts the severity of experimental autoimmune encephalomyelitis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | up-regulation |
| Mechanism/Pathway | Several recep- tors on other cells of the host have also been defined for Reg proteins (Reg1a- Exostosin- like 3 (Extl3); REG3A- EXTL3, Reg3γ- Extl3; REG3A- EGFR; Reg3β- gp130; Reg4- GPR37) though some are controversial |
