Basic information of IGKV4-1 :
| Official Symbol of Gene | IGKV4-1 |
| Species | Homo sapiens |
| Entrez Gene ID | 28908 |
| Official Full Name | immunoglobulin kappa variable 4-1 |
| Also known as | B3; IGKV41 |
| Gene Type | other |
| dbXrefs | Ensembl:ENSG00000211598 IMGT/GENE-DB:IGKV4-1; AllianceGenome:HGNC:5834 |
| Map Location | 2p11.2 |
Sample information of multiple sclerosis:
| Detected Sample | Brain |
| Sample Detail | cortical gray matter |
| Detected Method | qPCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | the Dutch Brain Bank, the Netherlands |
| Sample Size | 12 controls and 11 multiple sclerosis (MS) patients |
Literature information of multiple sclerosis :
| Pubmed ID | 19919606 |
| Year | 2010 |
| Title | Upregulation of immunoglobulin-related genes in cortical sections from multiple sclerosis patients |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | disease risk |
| Result | A Student's tâ€test (P<0.001) confirmed significant upregulation of IGKC, IGHG1 and IGKV41 in MS patients compared with controls. |
| Mechanism/Pathway | N/A |
