Basic information of MIR21 :
| Official Symbol of Gene | MIR21 |
| Species | Homo sapiens |
| Entrez Gene ID | 406991 |
| Official Full Name | microRNA 21 |
| Also known as | MIRN21; miR-21; miRNA21; hsa-mir-21 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000284190 MIM:611020; miRBase:MI0000077; AllianceGenome:HGNC:31586 |
| Map Location | 17q23.1 |
Sample information of multiple sclerosis:
| Detected Sample | cell-free cerebrospinal fluid |
| Sample Detail | N/A |
| Detected Method | TaqMan assays and Qpcr |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 46 relapse-onset MS patients |
Literature information of multiple sclerosis :
| Pubmed ID | 31727077 |
| Year | 2019 |
| Title | Analysis of miRNA signatures in CSF identifies upregulation of miR-21 and miR-146a/b in patients with multiple sclerosis and active lesions |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | In conclusion, overexpression of miR-21, miR-146a, and miR-146b in cell-free CSF were able to discriminate MS patients with Gd+ lesions in the MRI. |
| Mechanism/Pathway | N/A |
