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Basic information of CCL2 :

Official Symbol of Gene CCL2
Species Homo sapiens
Entrez Gene ID 6347
Official Full Name C-C motif chemokine ligand 2
Also known as HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30
Gene Type protein coding
dbXrefs Ensembl:ENSG00000108691 MIM:158105; AllianceGenome:HGNC:10618
Map Location 17q12

Sample information of multiple sclerosis:

Detected Sample blood
Sample Detail N/A
Detected Method PCR
Disease MS
Disease subtype RRMS,SPMS,PPMS
Population N/A
Sample Size 30MS,10 healthy donors

Literature information of multiple sclerosis :

Pubmed ID 19232440
Year 2009
Title Administration of a monomeric CCL2 variant to EAE mice inhibits inflammatory cell recruitment and protects from demyelination and axonal loss

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result CCL2 and CCR2 mRNA are upregulated during EAE/MS.
Mechanism/Pathway N/A