Basic information of SPP1 :
| Official Symbol of Gene | SPP1 |
| Species | Homo sapiens |
| Entrez Gene ID | 6696 |
| Official Full Name | secreted phosphoprotein 1 |
| Also known as | OPN; BNSP; BSPI; ETA-1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000118785 MIM:166490; AllianceGenome:HGNC:11255 |
| Map Location | 4q22.1 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | ELISA |
| Disease | MS |
| Disease subtype | RRMS |
| Population | N/A |
| Sample Size | Sixteen patients with clinically or laboratory supported definite RRMS |
Literature information of multiple sclerosis :
| Pubmed ID | 15342207 |
| Year | 2004 |
| Title | Osteopontin levels and increased disease activity in relapsing-remitting multiple sclerosis patients |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Although no robust relation between OPN and disease activity was observed, these data suggest that OPN levels are elevated prior to increased disease activity in RR MS patients. |
| Mechanism/Pathway | Osteopontin (OPN) has been identified as the most prominent cytokine-encoding gene expressed within multiple sclerosis (MS) lesions. |
