Basic information of CLEC16A :

Official Symbol of Gene	CLEC16A
Species	Homo sapiens
Entrez Gene ID	23274
Official Full Name	C-type lectin domain containing 16A
Also known as	Gop-1; KIAA0350
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000038532 MIM:611303; AllianceGenome:HGNC:29013
Map Location	16p13.13

Sample information of multiple sclerosis:

Detected Sample	blood
Sample Detail	N/A
Detected Method	PCR
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	MS; n =) and healthy controls (HC; n = 46

Literature information of multiple sclerosis :

Pubmed ID	25823473
Year	2015
Title	Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	CLEC16A expression is elevated in peripheral immune cells and brain tissue of multiple sclerosis patients.
Mechanism/Pathway	Together, we identify CLEC16A as a pivotal gene in multiple sclerosis that serves as a direct regulator of the human leukocyte antigen class II pathway in antigen-presenting cells.