Basic information of VEGFA :

Official Symbol of Gene	VEGFA
Species	Homo sapiens
Entrez Gene ID	7422
Official Full Name	vascular endothelial growth factor A
Also known as	VPF; VEGF; MVCD1
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000112715 MIM:192240; AllianceGenome:HGNC:12680
Map Location	6p21.1

Sample information of multiple sclerosis:

Detected Sample	blood,CSF
Sample Detail	N/A
Detected Method	RT-PCR
Disease	MS
Disease subtype	RRMS,SPMS
Population	N/A
Sample Size	RRMS (n = 128), SPMS (n = 55) and controls (n = 116)

Literature information of multiple sclerosis :

Pubmed ID	21573104
Year	2011
Title	The expression of VEGF-A is down regulated in peripheral blood mononuclear cells of patients with secondary progressive multiple sclerosis

Results of multiple sclerosis :

Expression	down-regulation
Risk type	Disease risk
Result	Expression of VEGF-A in CSF cells is reduced in MS patients compared to controls irrespective of disease course. In addition, SPMS patients display reduced VEGF-A mRNA expression in PBMC, which distinguish them from RRMS and controls.
Mechanism/Pathway	N/A