Basic information of IL12B :
| Official Symbol of Gene | IL12B |
| Species | Homo sapiens |
| Entrez Gene ID | 3593 |
| Official Full Name | interleukin 12B |
| Also known as | CLMF; NKSF; CLMF2; IMD28; IMD29; NKSF2; IL-12B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000113302 MIM:161561; AllianceGenome:HGNC:5970 |
| Map Location | 5q33.3 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | peripheral blood mononuclear cells |
| Detected Method | RT–PCR |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Iran |
| Sample Size | 145 MS patients and 200 healthy subjects |
Literature information of multiple sclerosis :
| Pubmed ID | 28276258 |
| Year | 2017 |
| Title | An interleukin 12 B single nucleotide polymorphism increases IL-12p40 production and is associated with increased disease susceptibility in patients with relapsing-remitting multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | The rs6887695 single-nucleotide polymorphism (SNP) in IL12B gene showed an association with susceptibility to MS |
| Mechanism/Pathway | N/A |
