Basic information of IL10 :
| Official Symbol of Gene | IL10 |
| Species | Homo sapiens |
| Entrez Gene ID | 3586 |
| Official Full Name | interleukin 10 |
| Also known as | CSIF; TGIF; GVHDS; IL-10; IL10A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000136634 MIM:124092; AllianceGenome:HGNC:5962 |
| Map Location | 1q32.1 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | CD25+ T cells |
| Detected Method | RT–PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size | 42 MS patients |
Literature information of multiple sclerosis :
| Pubmed ID | 33884734 |
| Year | 2021 |
| Title | CD4+ and CD25+ T-cell response to short-time interferon-beta therapy on IL10, IL23A and FOXP3 genes in multiple sclerosis patients |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | On the contemporary, IL10 gene expression of CD25+ T cells was gradually decreased, which was also statistically significant. |
| Mechanism/Pathway | Although this study did not mention any discrimination on genes we investigated here, it pointed out the minimal short-time effects on Th1/Th2 pathways which are known to be highly related to CD4+ and CD25+ T-cell metabolism |
