Basic information of ZMIZ1 :

Official Symbol of Gene	ZMIZ1
Species	Homo sapiens
Entrez Gene ID	57178
Official Full Name	zinc finger MIZ-type containing 1
Also known as	MIZ; RAI17; ZIMP10; NEDDFSA; TRAFIP10
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000108175 MIM:607159; AllianceGenome:HGNC:16493
Map Location	10q22.3

Sample information of multiple sclerosis:

Detected Sample	blood
Sample Detail	N/A
Detected Method	PCR
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	30 untreated MS and 29 healthy controls

Literature information of multiple sclerosis :

Pubmed ID	28063629
Year	2017
Title	The autoimmune risk gene ZMIZ1 is a vitamin D responsive marker of a molecular phenotype of multiple sclerosis

Results of multiple sclerosis :

Expression	down-regulation
Risk type	Disease risk
Result	In the Sydney PCR cohort, ZMIZ1 gene expression in whole blood samples was significantly reduced in MS compared to control.
Mechanism/Pathway	We propose that the expression of ZMIZ1 and the genes correlated with it identifies an arm of the immune response which affects MS disease susceptibility, is affected by MS therapies,and indicates a type of immune dysregulation which may identify personal response to therapy.