Basic information of ZFP36L1 :
| Official Symbol of Gene | ZFP36L1 |
| Species | Homo sapiens |
| Entrez Gene ID | 677 |
| Official Full Name | ZFP36 ring finger protein like 1 |
| Also known as | BRF1; ERF1; cMG1; ERF-1; Berg36; TIS11B; RNF162B |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000185650 MIM:601064; AllianceGenome:HGNC:1107 |
| Map Location | 14q24.1 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | N/A |
| Population | N/A |
| Sample Size |
49 treatment-na |
Literature information of multiple sclerosis :
| Pubmed ID | 25670004 |
| Year | 2015 |
| Title | Anti-inflammatory genes associated with multiple sclerosis: a gene expression study |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | Here, a gene expression analysis revealed that three of them, namely BACH2, PTGER4 and ZFP36L1, are down-regulated in MS patients' blood cells compared to healthy subjects. |
| Mechanism/Pathway | Interestingly, all these genes are involved in the immune system regulation with predominant anti-inflammatory role and their reduction could predispose to MS development. |
