Basic information of SELPLG :
| Official Symbol of Gene | SELPLG |
| Species | Homo sapiens |
| Entrez Gene ID | 6404 |
| Official Full Name | selectin P ligand |
| Also known as | CLA; CD162; PSGL1; PSGL-1 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000110876 MIM:600738; AllianceGenome:HGNC:10722 |
| Map Location | 12q24.11 |
Sample information of multiple sclerosis:
| Detected Sample | Peripheral blood |
| Sample Detail | N/A |
| Detected Method | PCR |
| Disease | MS |
| Disease subtype | PPMS |
| Population | N/A |
| Sample Size | n = 5–6 mice group |
Literature information of multiple sclerosis :
| Pubmed ID | 16039046 |
| Year | 2005 |
| Title | P-selectin glycoprotein ligand-1 variable number of tandem repeats (VNTR) polymorphism in patients with multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | As this allele has been demonstrated to have a very low efficiency in mediating lymphocyte binding to brain endothelium during attacks, its high frequency in PP-MS could be related to the absence of exacerbations in such patients |
| Mechanism/Pathway | P-selectin glycoprotein ligand-1 (PSGL-1) is an important adhesion molecule involved in lymphocyte recruitment into the brain |
