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Basic information of RT1-Da :

Official Symbol of Gene RT1-Da
Species Rattus norvegicus
Entrez Gene ID 294269
Official Full Name RT1 class II, locus Da
Also known as DA1; H2-Ea; RT1-u
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000032844 AllianceGenome:RGD:1593283
Map Location 20p12

Sample information of multiple sclerosis:

Detected Sample CNS tissue
Sample Detail N/A
Detected Method N/A
Disease EAE
Disease subtype N/A
Population DA rats
Sample Size n = 4-6 per diet group

Literature information of multiple sclerosis :

Pubmed ID 33304315
Year 2020
Title Effect of Vitamin D on Experimental Autoimmune Neuroinflammation Is Dependent on Haplotypes Comprising Naturally Occurring Allelic Variants of CIITA ( Mhc2ta)

Results of multiple sclerosis :

Expression down-regulation
Risk type Disease risk
Result we could observe reduced protein expression of MHC class II and CIITA in the CNS of the congenic rats fed with vitamin D supplemented diet.
Mechanism/Pathway N/A