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Basic information of Ndrg2 :

Official Symbol of Gene Ndrg2
Species Mus musculus
Entrez Gene ID 29811
Official Full Name N-myc downstream regulated gene 2
Also known as Ndr2; SYLD
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000004558 AllianceGenome:MGI:1352498
Map Location 14; 14 C2

Sample information of multiple sclerosis:

Detected Sample lumbar spinal cords
Sample Detail N/A
Detected Method western blotting,immunohistochemistry
Disease EAE
Disease subtype N/A
Population C57BL/6N
Sample Size WT mice (n = 7) / Ndrg2-/- mice (n = 7)

Literature information of multiple sclerosis :

Pubmed ID 29315585
Year 2018
Title Ndrg2 deficiency ameliorates neurodegeneration in experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result The NDRG2 expression levels were significantly increased in both the acute and chronic periods after EAE induction (Fig. 1a), when the levels of GFAP, which is the most commonly used marker of activated astrocytes, were also increased
Mechanism/Pathway N/A