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Basic information of NECTIN2 :

Official Symbol of Gene NECTIN2
Species Homo sapiens
Entrez Gene ID 5819
Official Full Name nectin cell adhesion molecule 2
Also known as HVEB; PRR2; CD112; PVRL2; PVRR2
Gene Type protein coding
dbXrefs Ensembl:ENSG00000130202 MIM:600798; AllianceGenome:HGNC:9707
Map Location 19q13.32

Sample information of multiple sclerosis:

Detected Sample PBMCs
Sample Detail N/A
Detected Method flow cytometry
Disease MS
Disease subtype N/A
Population N/A
Sample Size 20 MS patients / 20 controls

Literature information of multiple sclerosis :

Pubmed ID 15465608
Year 2004
Title The role of the polio virus receptor and the herpesvirus entry mediator B genes for the development of MS

Results of multiple sclerosis :

Expression No significance
Risk type Disease risk
Result The studies did not disclose any expression difference between MS patients and controls for the protein on peripheral blood monocytes.
Mechanism/Pathway HVEB mediates entry of neurotropic viruses to the brain.In the CNS, both receptors are structural CNS proteins and important for cellular interactions.