Basic information of IL25 :
| Official Symbol of Gene | IL25 |
| Species | Homo sapiens |
| Entrez Gene ID | 64806 |
| Official Full Name | interleukin 25 |
| Also known as | IL17E |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000166090 MIM:605658; AllianceGenome:HGNC:13765 |
| Map Location | 14q11.2 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | serum |
| Detected Method | ELISA |
| Disease | MS |
| Disease subtype | RRMS |
| Population | Iranian |
| Sample Size | 100 Relapsing-Remitting MS cases, and 100 healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 25143869 |
| Year | 2014 |
| Title | Molecular analysis of interleukin-25 exons 1 and 2 and its serum levels in Iranian patients with multiple sclerosis |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | These results demonstrate that serum levels of IL-25 are reduced in MS patients compared to controls. |
| Mechanism/Pathway | Considering the role of IL-25 in suppression of the effects of IL-17A and active phase of Experimental Autoimmune Encephalomyelitis (EAE) in vivo |
