Basic information of NFKB1 :

Official Symbol of Gene	NFKB1
Species	Homo sapiens
Entrez Gene ID	4790
Official Full Name	nuclear factor kappa B subunit 1
Also known as	KBF1; EBP-1; NF-kB; CVID12; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B1; NF-kappabeta
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000109320 MIM:164011; AllianceGenome:HGNC:7794
Map Location	4q24

Sample information of multiple sclerosis:

Detected Sample	white matter (NAWM)
Sample Detail	MS affected postmortem brain tissue
Detected Method	immunohistochemical
Disease	MS
Disease subtype	N/A
Population	N/A
Sample Size	4 MS patients / 4 patients without neurological complications

Literature information of multiple sclerosis :

Pubmed ID	11571785
Year	2001
Title	Upregulation of transcription factors controlling MHC expression in multiple sclerosis lesions

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	In microglial cells localized in normal control white matter, the NF-kB p50 and p65 subunits were expressed at weak to moderate levels.The NF-kB p50 and p65 subunits were moderately to strongly expressed in phagocytic macrophages in MS lesions .
Mechanism/Pathway	directly or indirectly regulate the expression of MHC class I and class II genes