Basic information of Ifng :
| Official Symbol of Gene | Ifng |
| Species | Mus musculus |
| Entrez Gene ID | 25712 |
| Official Full Name | interferon gamma |
| Also known as | If2f; IFNG2 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSRNOG00000007468 AllianceGenome:RGD:2866 |
| Map Location | 7q22 |
Sample information of multiple sclerosis:
| Detected Sample | brain |
| Sample Detail | N/A |
| Detected Method | flow cytometry |
| Disease | EAE |
| Disease subtype | N/A |
| Population | Brown-Norway (BN) rats |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 2456308 |
| Year | 1988 |
| Title | Inducibility of Ia molecules on keratinocytes reflects genetic control on astrocytes in the brain |
Results of multiple sclerosis :
| Expression | up-regulated |
| Risk type | Disease risk |
| Result | Keratinocytes of EAE-susceptible Lewis rats are induced to higher levels of Ia expression compared to relatively resistant Brown-Norway (BN) rats, independent of the dose of IFN-γ applied. |
| Mechanism/Pathway | It is now known that the product of Ir genes is the Ia molecule which functions by complexing with antigen in a manner that is recognized by T-cells. |
