Basic information of Ifng :

Official Symbol of Gene	Ifng
Species	Mus musculus
Entrez Gene ID	15978
Official Full Name	interferon gamma
Also known as	Ifg; If2f; IFN-g
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000055170 AllianceGenome:MGI:107656
Map Location	10 D2; 10 66.75 cM

Sample information of multiple sclerosis:

Detected Sample	N/A
Sample Detail	CD4 T cells
Detected Method	ELISA
Disease	EAE
Disease subtype	N/A
Population	C57BL/6 mice
Sample Size	three to four mice per group

Literature information of multiple sclerosis :

Pubmed ID	21151104
Year	2011
Title	T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt

Results of multiple sclerosis :

Expression	down-regulated
Risk type	Disease risk
Result	Collectively, there was a shift in the TH1-TH17 balance in the CNS of Tbx21/ mice during EAE characterized by a tendency toward the recruitment of TH17 cells and a significantly lower frequency and absolute number of IFN-γproducing CD4+ T cells.
Mechanism/Pathway	TH17 cells produce IL-17A, IL-17F, IL-21 and IL-22