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Basic information of Mog :

Official Symbol of Gene Mog
Species Rattus norvegicus
Entrez Gene ID 24558
Official Full Name myelin oligodendrocyte glycoprotein
Also known as N/A
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000000775 AllianceGenome:RGD:3102
Map Location 20p12

Sample information of multiple sclerosis:

Detected Sample serum and CSF
Sample Detail N/A
Detected Method enzyme-linked immunosorbent assay
Disease EAE
Disease subtype N/A
Population DA and PVG.1AV1 rats
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 23784360
Year 2013
Title Anti-MOG antibodies are under polygenic regulation with the most significant control coming from the C-type lectin-like gene locus

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result Sick rats displayed higher levels of anti-MOG IgG, IgG1, IgG2b and IgG2c at the onset of disease in both crosses. During the later phase of EAE, the anti-MOG IgG1 response became higher in healthy rats, whereas total IgG and IgG2b levels remained higher in affected rats compared with healthy rats.
Mechanism/Pathway N/A