Basic information of LEP :
| Official Symbol of Gene | LEP |
| Species | Homo sapiens |
| Entrez Gene ID | 3952 |
| Official Full Name | leptin |
| Also known as | OB; OBS; LEPD |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000174697 MIM:164160; AllianceGenome:HGNC:6553 |
| Map Location | 7q32.1 |
Sample information of multiple sclerosis:
| Detected Sample | serum |
| Sample Detail | N/A |
| Detected Method | ELISA |
| Disease | MS |
| Disease subtype | RRMS |
| Population | N/A |
| Sample Size | 44 MS patients / 44 controls |
Literature information of multiple sclerosis :
| Pubmed ID | 30219158 |
| Year | 2018 |
| Title | Gender-Specific Association of Leptin and Adiponectin Genes With Multiple Sclerosis |
Results of multiple sclerosis :
| Expression | no difference |
| Risk type | Disease risk |
| Result | Leptin levels did not show significant differences between studied groups. |
| Mechanism/Pathway |
MS is mainly considered a Th1-mediated inflammatory disease,although recent studies postulate a vital role for helper T cells-17 (Th17 cells) in the pathogenesis of the disease .Therefore, the pathogenesis of MS is influenced by factors that affect the deviation of na |
