Basic information of Il17a :

Official Symbol of Gene	Il17a
Species	Mus musculus
Entrez Gene ID	16171
Official Full Name	interleukin 17A
Also known as	Il17; Ctla8; IL-17; Ctla-8; IL-17A
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000025929 AllianceGenome:MGI:107364
Map Location	1; 1 A4

Sample information of multiple sclerosis:

Detected Sample	N/A
Sample Detail	CD4 T cells
Detected Method	ELISA
Disease	EAE
Disease subtype	N/A
Population	C57BL/6 mice
Sample Size	three to four mice per group

Literature information of multiple sclerosis :

Pubmed ID	21151104
Year	2011
Title	T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt

Results of multiple sclerosis :

Expression	up-regulated
Risk type	Disease risk
Result	Moreover, CD4+ T cells isolated from the CNS of Tbx21/ mice secreted significantly more IL-17A than did wild-type CD4+ T cells at day 17 after immunization.
Mechanism/Pathway	TH17 cells produce IL-17A, IL-17F, IL-21 and IL-22