Basic information of NFKB1 :

Official Symbol of Gene	NFKB1
Species	Homo sapiens
Entrez Gene ID	4790
Official Full Name	nuclear factor kappa B subunit 1
Also known as	KBF1; EBP-1; NF-kB; CVID12; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B1; NF-kappabeta
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000109320 MIM:164011; AllianceGenome:HGNC:7794
Map Location	4q24

Sample information of multiple sclerosis:

Detected Sample	PBMC
Sample Detail	N/A
Detected Method	flow cytometry
Disease	MS
Disease subtype	RRMS
Population	N/A
Sample Size	25 MS treated / 11 untreated MS / 34 healthy control

Literature information of multiple sclerosis :

Pubmed ID	26062845
Year	2015
Title	Genetic variants associated with autoimmunity drive NFκB signaling and responses to inflammatory stimuli

Results of multiple sclerosis :

Expression	down-regulation
Risk type	Disease risk
Result	We found that nave CD4 cells from patients with MS exhibit significantly higher phospho-p65 NFκB than those from age-matched healthy control donors .
Mechanism/Pathway	NFκB was one of the first transcription factors identified and is a central regulator of inflammation.