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Basic information of Ifng :

Official Symbol of Gene Ifng
Species Mus musculus
Entrez Gene ID 15978
Official Full Name interferon gamma
Also known as Ifg; If2f; IFN-g
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000055170 AllianceGenome:MGI:107656
Map Location 10 D2; 10 66.75 cM

Sample information of multiple sclerosis:

Detected Sample optic nerve
Sample Detail N/A
Detected Method ELISA
Disease EAE
Disease subtype N/A
Population C57BL/6 mice
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 20428790
Year 2010
Title Alteration of T helper cell subsets in the optic nerve of experimental autoimmune encephalomyelitis

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result The overall result demonstrates a significant increase in the expression of inflammatory cytokines in the optic nerve of the EAE mouse.
Mechanism/Pathway IFN-gamma may aggravate inflammatory injury during the peak stage of optic neuritis.