Basic information of Il17a :
| Official Symbol of Gene | Il17a |
| Species | Mus musculus |
| Entrez Gene ID | 16171 |
| Official Full Name | interleukin 17A |
| Also known as | Il17; Ctla8; IL-17; Ctla-8; IL-17A |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000025929 AllianceGenome:MGI:107364 |
| Map Location | 1; 1 A4 |
Sample information of multiple sclerosis:
| Detected Sample | optic nerve |
| Sample Detail | N/A |
| Detected Method | ELISA |
| Disease | EAE |
| Disease subtype | N/A |
| Population | C57BL/6 mice |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 20428790 |
| Year | 2010 |
| Title | Alteration of T helper cell subsets in the optic nerve of experimental autoimmune encephalomyelitis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | The overall result demonstrates a significant increase in the expression of inflammatory cytokines in the optic nerve of the EAE mouse. |
| Mechanism/Pathway | IL-17 may mediate inflammatory pathogenicity at the early stage of optic neuritis. |
