Basic information of Tbx21 :
| Official Symbol of Gene | Tbx21 |
| Species | Mus musculus |
| Entrez Gene ID | 57765 |
| Official Full Name | T-box 21 |
| Also known as | TBT1; Tbet; Tblym |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000001444 AllianceGenome:MGI:1888984 |
| Map Location | 11; 11 D |
Sample information of multiple sclerosis:
| Detected Sample | N/A |
| Sample Detail | CD4 T cells |
| Detected Method | ELISA |
| Disease | EAE |
| Disease subtype | N/A |
| Population | C57BL/6 mice |
| Sample Size | n = 3 |
Literature information of multiple sclerosis :
| Pubmed ID | 35121767 |
| Year | 2022 |
| Title | Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc |
Results of multiple sclerosis :
| Expression | down-regulated |
| Risk type | Disease risk |
| Result | high zinc aspartate concentrations was signifcantly impaired indicated by reduced expression of the T1 transcription factor Tbet and the T1 signature cytokine IFN-γ as well as of the cytokines IL-2 and TNF-αT1 cells and transferring them into C57BL/6 recipient mice. |
| Mechanism/Pathway | transcription factor |
