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Basic information of Stat3 :

Official Symbol of Gene Stat3
Species Mus musculus
Entrez Gene ID 20848
Official Full Name signal transducer and activator of transcription 3
Also known as Aprf; 1110034C02Rik
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000004040 AllianceGenome:MGI:103038
Map Location 11 D; 11 63.82 cM

Sample information of multiple sclerosis:

Detected Sample brain
Sample Detail N/A
Detected Method immunoblotting
Disease EAE
Disease subtype N/A
Population C57BL/6 mice
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 25113558
Year 2014
Title PERK-dependent activation of JAK1 and STAT3 contributes to endoplasmic reticulum stress-induced inflammation

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result increased activation-associated phosphorylation of STAT3
Mechanism/Pathway the presence of ER stress in the CNS during EAE