Basic information of NPY :
| Official Symbol of Gene | NPY |
| Species | Homo sapiens |
| Entrez Gene ID | 4852 |
| Official Full Name | neuropeptide Y |
| Also known as | PYY4 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000122585 MIM:162640; AllianceGenome:HGNC:7955 |
| Map Location | 7p15.3 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | serum |
| Detected Method | ELISA |
| Disease | MS |
| Disease subtype | RRMS,PRMS |
| Population | Jordan |
| Sample Size | 67 MS patients: 61 relapsing-remitting MS (RR-MS) and 6 progressive MS (PR-MS), and 67 healthy controls. |
Literature information of multiple sclerosis :
| Pubmed ID | 37013432 |
| Year | 2023 |
| Title | Alpha Calcitonin Gene-related Peptide, Neuropeptide Y, and Substance P as Biomarkers for Diagnosis and Disease Activity and Severity in Multiple Sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Serum NPY level was significantly higher in RR-MS and PR-MS than in healthy controls (p < 0.001 and p = 0.001, respectively), and it was lower in patients with mild or moderate/severe disease than in healthy controls (p < 0.001) |
| Mechanism/Pathway | N/A |
