Basic information of TACR1 :
| Official Symbol of Gene | TACR1 |
| Species | Homo sapiens |
| Entrez Gene ID | 6869 |
| Official Full Name | tachykinin receptor 1 |
| Also known as | SPR; NK1R; NKIR; TAC1R |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000115353 MIM:162323; AllianceGenome:HGNC:11526 |
| Map Location | 2p12 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | serum |
| Detected Method | ELISA |
| Disease | MS |
| Disease subtype | RRMS,PRMS |
| Population | Jordan |
| Sample Size | 67 MS patients: 61 relapsing-remitting MS (RR-MS) and 6 progressive MS (PR-MS), and 67 healthy controls. |
Literature information of multiple sclerosis :
| Pubmed ID | 37013432 |
| Year | 2023 |
| Title | Alpha Calcitonin Gene-related Peptide, Neuropeptide Y, and Substance P as Biomarkers for Diagnosis and Disease Activity and Severity in Multiple Sclerosis |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | Significant inverse correlations were found between SP level and MS disease duration (r = -0.279, p = 0.022) and duration of current DMT |
| Mechanism/Pathway | N/A |
