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Basic information of Ifng :

Official Symbol of Gene Ifng
Species Mus musculus
Entrez Gene ID 15978
Official Full Name interferon gamma
Also known as Ifg; If2f; IFN-g
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000055170 AllianceGenome:MGI:107656
Map Location 10 D2; 10 66.75 cM

Sample information of multiple sclerosis:

Detected Sample N/A
Sample Detail CD4 T cells
Detected Method ELISA
Disease EAE
Disease subtype N/A
Population C57BL/6 mice
Sample Size n = 3

Literature information of multiple sclerosis :

Pubmed ID 35121767
Year 2022
Title Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc

Results of multiple sclerosis :

Expression down-regulated
Risk type Disease risk
Result high zinc aspartate concentrations was signifcantly impaired indicated by reduced expression of the T1 transcription factor Tbet and the T1 signature cytokine IFN-γ as well as of the cytokines IL-2 and TNF-αT1 cells and transferring them into C57BL/6 recipient mice.
Mechanism/Pathway inflammatory cytokines