Basic information of Mst1r :
| Official Symbol of Gene | Mst1r |
| Species | Mus musculus |
| Entrez Gene ID | 19882 |
| Official Full Name | macrophage stimulating 1 receptor (c-met-related tyrosine kinase) |
| Also known as | Fv2; Ron; STK; Fv-2; PTK8; CD136; CDw136; p185-Ron |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000032584 AllianceGenome:MGI:99614 |
| Map Location | 9 59.07 cM; 9 F1 |
Sample information of multiple sclerosis:
| Detected Sample | Brain tissue |
| Sample Detail | N/A |
| Detected Method | Immunoblot analysis |
| Disease | EAE |
| Disease subtype | N/A |
| Population | female 129/SvEv mice |
| Sample Size | N/A |
Literature information of multiple sclerosis :
| Pubmed ID | 15929040 |
| Year | 2005 |
| Title | RON-Regulated Innate Immunity Is Protective in an Animal Model of Multiple Sclerosis |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | Neurological disease in RON-deficient animals showed a more rapid onset with overall worsened severity, together with exacerbated demyelination, axonal injury, and neuroinflammation after EAE induction |
| Mechanism/Pathway | RON Receptor Expression Is Reduced |
