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Basic information of MST1R :

Official Symbol of Gene MST1R
Species Homo sapiens
Entrez Gene ID 4486
Official Full Name macrophage stimulating 1 receptor
Also known as RON; SEA; PTK8; CD136; NPCA3; CDw136; p185-Ron
Gene Type protein coding
dbXrefs Ensembl:ENSG00000164078 MIM:600168; AllianceGenome:HGNC:7381
Map Location 3p21.31

Sample information of multiple sclerosis:

Detected Sample Brain tissue
Sample Detail frontal white matter
Detected Method Immunoblot analysis
Disease MS
Disease subtype N/A
Population Neurovirology Laboratory Brain Bank, Calgary, AB, Canada
Sample Size control, n = 13 and MS, n = 14

Literature information of multiple sclerosis :

Pubmed ID 15929040
Year 2005
Title RON-Regulated Innate Immunity Is Protective in an Animal Model of Multiple Sclerosis

Results of multiple sclerosis :

Expression down-regulation
Risk type Disease risk
Result RON mRNA and protein abundance in the CNS were diminished in both MS patients and the MS animal model, experimental autoimmune encephalomyelitis (EAE)
Mechanism/Pathway RON Receptor Expression Is Reduced