Basic information of APOE :

Official Symbol of Gene	APOE
Species	Homo sapiens
Entrez Gene ID	348
Official Full Name	apolipoprotein E
Also known as	AD2; LPG; APO-E; ApoE4; LDLCQ5
Gene Type	protein coding
dbXrefs	Ensembl:ENSG00000130203 MIM:107741; AllianceGenome:HGNC:613
Map Location	19q13.32

Sample information of multiple sclerosis:

Detected Sample	N/A
Sample Detail	formalin-fixed paraffinembedded tissue
Detected Method	Immunohistochemistry
Disease	MS
Disease subtype	N/A
Population	the Neuropathology Department at the Institute of Neurological Sciences in Glasgow 10888365
Sample Size	71 archival cases of multiple sclerosis and 41 controls

Literature information of multiple sclerosis :

Pubmed ID	10888365
Year	2000
Title	Differential DM20 mRNA Expression Distinguishes Two Distinct Patterns of Spontaneous Recovery From Murine Autoimmune Encephalomyelitis

Results of multiple sclerosis :

Expression	up-regulation
Risk type	Disease risk
Result	ApoE immunoreactivity was increased in demyelinated areas compared with control white matter.
Mechanism/Pathway	apoE is involved in the trafficking of lipid in MS