Basic information of CLEC16A :
| Official Symbol of Gene | CLEC16A |
| Species | Homo sapiens |
| Entrez Gene ID | 23274 |
| Official Full Name | C-type lectin domain containing 16A |
| Also known as | Gop-1; KIAA0350 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000038532 MIM:611303; AllianceGenome:HGNC:29013 |
| Map Location | 16p13.13 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | PBMCs |
| Detected Method | WB |
| Disease | MS |
| Disease subtype | CIS,RRMS |
| Population | Dutch |
| Sample Size | 41 |
Literature information of multiple sclerosis :
| Pubmed ID | 32641384 |
| Year | 2020 |
| Title |
The Role of Autoimmunity-Related Gene CLEC16A in the B Cell Receptor |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | CLEC16A participates in the BCR-dependent HLA-II pathway in human B cells and that this regulation is impaired during MS disease onset. . |
| Mechanism/Pathway | The abundance of CLIP already on naive B cells of MS patients may point to a chronically induced stage and a new mechanism underlying B cell–mediated autoimmune diseases such as MS |
