Basic information of Dock10 :
| Official Symbol of Gene | Dock10 |
| Species | Mus musculus |
| Entrez Gene ID | 210293 |
| Official Full Name | dedicator of cytokinesis 10 |
| Also known as | Jr4; Jr5; ZIZ3; Zizimin3; mKIAA0694; 9330153B10Rik; A630054M16Rik |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSMUSG00000038608 AllianceGenome:MGI:2146320 |
| Map Location | 1; 1 C5 |
Sample information of multiple sclerosis:
| Detected Sample | retina，optic nerves |
| Sample Detail | N/A |
| Detected Method | ELISAã€Immunofluorescence |
| Disease | EAE |
| Disease subtype | N/A |
| Population | C57BL/6 |
| Sample Size | EAE mice (n=11 for WT; n=7 for DOCK9-/-; n=6 for DOCK10-/-; and n=6 for DOCK11-/- |
Literature information of multiple sclerosis :
| Pubmed ID | 32241915 |
| Year | 2020 |
| Title | Roles of the DOCK-D family proteins in a mouse model of neuroinflammation |
Results of multiple sclerosis :
| Expression | down-regulation |
| Risk type | Disease risk |
| Result | EAE severity was ameliorated in DOCK10-/- mice |
| Mechanism/Pathway | innate immunity and neuroinflammation |
