Basic information of Rnf128 :

Official Symbol of Gene	Rnf128
Species	Mus musculus
Entrez Gene ID	66889
Official Full Name	ring finger protein 128
Also known as	GRAIL; Greul1; 1300002C13Rik
Gene Type	protein coding
dbXrefs	Ensembl:ENSMUSG00000031438 AllianceGenome:MGI:1914139
Map Location	X; X F1

Sample information of multiple sclerosis:

Detected Sample	CNS tissues
Sample Detail	N/A
Detected Method	WB
Disease	EAE
Disease subtype	N/A
Population	C57BL6/J，SJL/J
Sample Size	N/A

Literature information of multiple sclerosis :

Pubmed ID	31362466
Year	2019
Title	NK Cell Induced T Cell Anergy Depends on GRAIL Expression

Results of multiple sclerosis :

Expression	down-regulation
Risk type	Disease risk
Result	suppressed PLP-induced T cell proliferation by enhancing T cell expression of GRAIL as GRAIL downregulation restored T cell proliferation
Mechanism/Pathway	HINT1/Hsp70 treatment generated regulatory NK cells characterized by expression of GRAIL.