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Basic information of Mbp :

Official Symbol of Gene Mbp
Species Rattus norvegicus
Entrez Gene ID 24547
Official Full Name myelin basic protein
Also known as Mbps
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000016516 AllianceGenome:RGD:3054
Map Location 18q12.3

Sample information of multiple sclerosis:

Detected Sample spinal cord
Sample Detail N/A
Detected Method Immunohistochemistry
Disease EAE
Disease subtype N/A
Population Lewis rats
Sample Size 50

Literature information of multiple sclerosis :

Pubmed ID 35072933
Year 2022
Title Therapeutic Potential of Combined Therapy of Vitamin A and Vitamin C in the Experimental Autoimmune Encephalomyelitis (EAE) in Lewis Rats

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result combined therapy of vitamins A and C effectively protect myelin damage in EAE model via increasing MBP level and BDNF as a crucial protein in myelin repair
Mechanism/Pathway N/A