Basic information of CXCL12 :
| Official Symbol of Gene | CXCL12 |
| Species | Homo sapiens |
| Entrez Gene ID | 6387 |
| Official Full Name | C-X-C motif chemokine ligand 12 |
| Also known as | IRH; PBSF; SDF1; TLSF; TPAR1; SCYB12 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000107562 MIM:600835; AllianceGenome:HGNC:10672 |
| Map Location | 10q11.21 |
Sample information of multiple sclerosis:
| Detected Sample | peripheral blood |
| Sample Detail | serum |
| Detected Method | ELISA |
| Disease | MS |
| Disease subtype | RRMSã€SPMS |
| Population | individuals with MS |
| Sample Size | RRMS (n=24) and SPMS (n=28) |
Literature information of multiple sclerosis :
| Pubmed ID | 27519689 |
| Year | 2016 |
| Title | Identification of gene expression patterns crucially involved in experimental autoimmune encephalomyelitis and multiple sclerosis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | we detected increased protein CXCL12 serum levels in both individuals with RRMS and SPMS compared to controls |
| Mechanism/Pathway | N/A |
