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Basic information of Mir23b :

Official Symbol of Gene Mir23b
Species Mus musculus
Entrez Gene ID 387217
Official Full Name microRNA 23b
Also known as Mirn23b; mmu-mir-23b
Gene Type ncRNA
dbXrefs Ensembl:ENSMUSG00000065599 miRBase:MI0000141; AllianceGenome:MGI:2676898
Map Location 13; 13 B3

Sample information of multiple sclerosis:

Detected Sample Brain and lumbar spinal cords
Sample Detail N/A
Detected Method immunohistochemistry;WB;ELISA
Disease EAE
Disease subtype N/A
Population C57BL/6
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 29275848
Year 2018
Title miR-23b Suppresses Leukocyte Migration and Pathogenesis of Experimental Autoimmune Encephalomyelitis by Targeting CCL7

Results of multiple sclerosis :

Expression down-regulation
Risk type Disease risk
Result miR-23b reduced the severity of EAE by inhibiting the migration of pathogenic T cells to the CNS rather than diminishing the encephalitogenesis of T cells.
Mechanism/Pathway inhibiting the migration of pathogenic T cells to the CNS