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Basic information of Mapk14 :

Official Symbol of Gene Mapk14
Species Mus musculus
Entrez Gene ID 26416
Official Full Name mitogen-activated protein kinase 14
Also known as N/A
Gene Type protein coding
dbXrefs Ensembl:ENSMUSG00000053436 AllianceGenome:MGI:1346865
Map Location 17 A3.3; 17 14.85 cM

Sample information of multiple sclerosis:

Detected Sample spinal cord
Sample Detail N/A
Detected Method Western blot
Disease EAE
Disease subtype N/A
Population C57BL/6J
Sample Size N/A

Literature information of multiple sclerosis :

Pubmed ID 22637476
Year 2012
Title Mechanism for p38-mediated Experimental Autoimmune Encephalomyelitis

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result oral administration of a highly specific p38 inhibitor (UR5269) to WT mice at the onset ofEAE markedly suppressed the progression of EAE compared with a vehicle group.
Mechanism/Pathway through IL-17 induction.