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Basic information of CLDN11 :

Official Symbol of Gene CLDN11
Species Homo sapiens
Entrez Gene ID 8514
Official Full Name claudin 11
Also known as OSP; OTM; HLD22
Gene Type protein coding
dbXrefs Ensembl:ENSG00000013297 MIM:601326; AllianceGenome:HGNC:8514
Map Location 3q26.2

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail N/A
Detected Method ELISA
Disease MS
Disease subtype N/A
Population N/A
Sample Size 13 men MS cases and 15 men controls

Literature information of multiple sclerosis :

Pubmed ID 26768647
Year 2016
Title Leukocyte Gene Expression and Plasma Concentration in Multiple Sclerosis: Alteration of Transforming Growth Factor-βs, Claudin-11, and Matrix Metalloproteinase-2

Results of multiple sclerosis :

Expression N/A
Risk type Disease risk
Result Detection of proteins by ELISA showed no significant differences in plasma concentration of MMP-2 and Claaudin-11 between two groups
Mechanism/Pathway Leukocytes penetration into the blood-brain barrier is related to several factors, such as, the conversion of leukocyte gene expression or plasma characteristics