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Basic information of TGFB1 :

Official Symbol of Gene TGFB1
Species Homo sapiens
Entrez Gene ID 11766
Official Full Name transforming growth factor beta 1
Also known as CED; LAP; DPD1; TGFB; IBDIMDE; TGFbeta; TGF-beta1
Gene Type protein coding
dbXrefs Ensembl:ENSG00000105329 MIM:190180; AllianceGenome:HGNC:11766
Map Location 19q13.2

Sample information of multiple sclerosis:

Detected Sample peripheral blood
Sample Detail N/A
Detected Method ELISA
Disease MS
Disease subtype N/A
Population N/A
Sample Size 13 men MS cases and 15 men controls

Literature information of multiple sclerosis :

Pubmed ID 26768647
Year 2016
Title Leukocyte Gene Expression and Plasma Concentration in Multiple Sclerosis: Alteration of Transforming Growth Factor-βs, Claudin-11, and Matrix Metalloproteinase-2

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result the plasma levels of TGF-β1、TGF-β2 and TGF-β3 were significantly elevated in MS patients
Mechanism/Pathway Leukocytes penetration into the blood-brain barrier is related to several factors, such as, the conversion of leukocyte gene expression or plasma characteristics