Basic information of IL27 :
| Official Symbol of Gene | IL27 |
| Species | Homo sapiens |
| Entrez Gene ID | 246778 |
| Official Full Name | interleukin 27 |
| Also known as | p28; IL30; IL-27; IL27A; IL-27A; IL27p28 |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSG00000197272 MIM:608273; AllianceGenome:HGNC:19157 |
| Map Location | 16p12.1-p11.2 |
Sample information of multiple sclerosis:
| Detected Sample | blood |
| Sample Detail | peripheral blood mononuclear cells |
| Detected Method | ELISA |
| Disease | MS |
| Disease subtype | PPMS, RRMS, SPMS |
| Population | N/A |
| Sample Size | 45 newly-diagnosed MS patients and 45 age- and gender-matched healthy controls |
Literature information of multiple sclerosis :
| Pubmed ID | 25780887 |
| Year | 2015 |
| Title | Cytokines gene expression in newly diagnosed multiple sclerosis patients |
Results of multiple sclerosis :
| Expression | down-regulated |
| Risk type | Disease risk |
| Result | The plasma levels of IL-10, IL-27 and TGF-β in MS patients were significantly lower than healthy controls (p<0.001, p<0.001, and p=0.013). |
| Mechanism/Pathway | inhibitory cytokines |
