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Basic information of Csf1 :

Official Symbol of Gene Csf1
Species Rattus norvegicus
Entrez Gene ID 621063
Official Full Name colony stimulating factor 1
Also known as N/A
Gene Type protein coding
dbXrefs Ensembl:ENSRNOG00000018659 AllianceGenome:RGD:621063
Map Location 2q34

Sample information of multiple sclerosis:

Detected Sample spinal cord
Sample Detail N/A
Detected Method Western Blotting
Disease EAE
Disease subtype N/A
Population Male Lewis rats
Sample Size n = 3 mice group

Literature information of multiple sclerosis :

Pubmed ID 8450228
Year 1993
Title Expression of CSF-1, c-fms, and MCP-1 in the central nervous system of rats with experimental allergic encephalomyelitis

Results of multiple sclerosis :

Expression up-regulation
Risk type Disease risk
Result CSF-1 protein was also detected in the central nervous system at the height of clinical disease
Mechanism/Pathway within the CNS, the production of factors that recruit macrophages from the periphery into the spinal cord and lead to the expansion and activation of these cells are an important component of the encephalitogenic process.