Basic information of Csf1r :
| Official Symbol of Gene | Csf1r |
| Species | Rattus norvegicus |
| Entrez Gene ID | 2425 |
| Official Full Name | colony stimulating factor 1 receptor |
| Also known as | c-fms; mrfms; CSF-1R; CSF-1-R; M-CSF-R |
| Gene Type | protein coding |
| dbXrefs | Ensembl:ENSRNOG00000018414 AllianceGenome:RGD:2425 |
| Map Location | 18q12.1 |
Sample information of multiple sclerosis:
| Detected Sample | spinal cord |
| Sample Detail | N/A |
| Detected Method | Western Blotting |
| Disease | EAE |
| Disease subtype | N/A |
| Population | Male Lewis rats |
| Sample Size | n = 3 mice group |
Literature information of multiple sclerosis :
| Pubmed ID | 8450228 |
| Year | 1993 |
| Title | Expression of CSF-1, c-fms, and MCP-1 in the central nervous system of rats with experimental allergic encephalomyelitis |
Results of multiple sclerosis :
| Expression | up-regulation |
| Risk type | Disease risk |
| Result | Unlike CSF-1 message levels, c-fms expression remained elevated after resolution of the acute disease episode |
| Mechanism/Pathway | within the CNS, the production of factors that recruit macrophages from the periphery into the spinal cord and lead to the expansion and activation of these cells are an important component of the encephalitogenic process. |
